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pentobarbital will minimize the extent or effect of etravirine by affecting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Observe.Keep an eye on Carefully (one)pentobarbital will lessen the level or effect of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Lack of, or diminished reaction to tofa